
2250 W. Holcombe Blvd., Houston, TX 77030
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SALADS
Antipasto

Genoa salami, pepperoni, provolone cheese, fresh mozzarella cheese, mortadella ham, turkey, romaine lettuce and fresh garden vegetables served with balsamic vinaigrette.
$10.95
Garden Salad

Romaine lettuce, red onions, bell peppers, sliced cucumber, olives, roma tomatoes, red cabbage and carrots.
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Greek Salad

Romaine lettuce served with feta cheese and fresh garden vegetables.
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Caesar Salad

Romaine lettuce tossed in our homemade Caesar dressing.
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Mediterranean Salad

Romaine lettuce, fresh garden vegetables, pecans, sun-dried tomatoes artichoke hearts and Gorgonzola cheese served with balsamic vinaigrette.
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Grilled Chicken Salad

Grilled chicken breast served on fresh-cut romaine lettuce and fresh garden vegetables.
$10.95

HOUSE SPECIALS
Gluten Free option is available!
Med Center Special

Home-made meatballs, red onions, bell peppers, jalapenos, mozzarella cheese and pizza sauce.
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Margherita

Garden tomatoes, basil, garlic, olive oil, & mozzarella cheese.
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Greek

Garden tomatoes, feta cheese, black olives, olive oil, & mozzarella cheese.
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Four Cheese

Ricotta cheese, Romano cheese, feta cheese, & mozzarella cheese.
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Hawaiian

Pineapple, Canadian bacon, mozzarella cheese and pizza sauce.
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Two Guys Supreme

Pepperoni, Canadian bacon, hamburger, sausage, onions, bell peppers, mushrooms, black olives, & mozzarella cheese.
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Meat Lovers Deluxe

Pepperoni, Canadian bacon, salami, sausage, hamburger, & mozzarella cheese.
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Midtown Special

Hamburger, spicy sausage, bell peppers, red onions, & mozzarella cheese.
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Italian Prosciutto

Prosciutto, basil, garlic, Romano cheese, garden tomatoes, olive oil, & mozzarella cheese.
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Pollo Italian

Grilled chicken, tomatoes, garlic, black pepper, olive oil, feta cheese, spinach, & mozzarella cheese.
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Veggie Lovers

Tomatoes, garlic, bell peppers, green & black olives, red onions, mushrooms, spinach, & mozzarella cheese.
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Spinach Chicken Alfredo

Grilled chicken, spinach, onions, Alfredo sauce, feta cheese, & mozzarella cheese.
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Venitan

Pepperoni, ricotta cheese, spicy sausage, sun-dried tomatoes, & mozzarella cheese.
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Artichoke Vegetarian

Artichoke hearts, red onions, mushrooms, tomatoes, garlic, spinach, olive oil, & mozzarella cheese.
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Pesto Chicken Deluxe

Grilled chicken, tomatoes, spinach, feta cheese, garlic, pesto sauce, & mozzarella cheese.
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J&J Special

Pepperoni, feta cheese, mushrooms, tomatoes, & mozzarella cheese.
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University Special

Extra pepperoni, & extra mozzarella.
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The PortaBello

Baby portabella mushrooms, mushrooms, parsley, basil, & mozzarella cheese.
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Buffalo Chicken

Buffalo sauce, grilled chicken, garlic, & mozzarella cheese.
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Chicken Tikka Pizza

Chicken, bell peppers, onions, and jalapenos.
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Chicken Alfredo

Grilled chicken, onions, Alfredo sauce, feta cheese, & mozzarella cheese.
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Spinach Alfredo

Spinach, onions, Alfredo sauce, feta cheese, & mozzarella cheese.
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CALZONES
Pepperoni & Sausage Calzone

Pepperoni, sausage and mozzarella cheese.
$10.95
Spinach Calzone

Spinach, roma tomatoes, olives, mushrooms, & mozzarella cheese.
$10.95
The Stromboli

Pepperoni, sausage, mushrooms, black olives, bell peppers, ground beef, mozzarella cheese.
$10.95
Mediterranean Calzone

Spinach, roma tomatoes, feta cheese, garlic, black olives, mozzarella cheese.
$10.95
Meatball Calzone

Meatballs and mozzarella cheese.
$10.95
Create Your Own Calzone

Up to (3) toppings of your choice.
$10.95

SUBS
All subs are served on French bread. Mustard and mayo added upon request.
Vegetarian Sub

Red onion, green peppers, mushrooms, provolone cheese, olive dressing, cucumbers, romaine lettuce, & black olives.
$7.95
Italian Sub

Ham, salami, lettuce, tomatoes, & provolone cheese.
$8.95
Turkey Sub

Turkey, provolone cheese, & olive dressing.
$8.95
Super Deli Sub

Ham, salami, turkey, provolone cheese, romaine lettuce, & tomatoes.
$9.95
Meatball Sub

Italian meatballs with meat sauce, & mozzarella cheese.
$8.95

HALAL
Traditional Garlic Bread (Halal)

$3.50
Traditional Garlic Bread with Cheese (Halal)

$4.95
Build Your Own - Deck Oven Cheese Pizza (Halal)

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Med Center Special (Halal)

Home-made meatballs, red onions, bell peppers, jalapenos, mozzarella cheese and pizza sauce.
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Margherita (Halal)

Garden tomatoes, basil, garlic, olive oil, & mozzarella cheese.
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Four Cheese (Halal)

Ricotta cheese, Romano cheese, feta cheese, & mozzarella cheese.
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Pollo Italian (Halal)

Grilled chicken, tomatoes, garlic, black pepper, olive oil, feta cheese, spinach, & mozzarella cheese.
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Veggie Lovers (Halal)

Tomatoes, garlic, bell peppers, green & black olives, red onions, mushrooms, spinach, & mozzarella cheese.
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Spinach Chicken Alfredo (Halal)

Grilled chicken, spinach, onions, Alfredo sauce, feta cheese, & mozzarella cheese.
Click For Price
Artichoke Vegetarian (Halal)

Artichoke hearts, red onions, mushrooms, tomatoes, garlic, spinach, olive oil, & mozzarella cheese.
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Pesto Chicken Deluxe (Halal)

Grilled chicken, tomatoes, spinach, feta cheese, garlic, pesto sauce, & mozzarella cheese.
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The PortaBello (Halal)

Baby portabella mushrooms, mushrooms, parsley, basil, & mozzarella cheese.
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Buffalo Chicken (Halal)

Buffalo sauce, grilled chicken, garlic, & mozzarella cheese.
Click For Price
Chicken Tikka Pizza (Halal)

Chicken, bell peppers, onions, and jalapenos.
Click For Price
Chicken Alfredo (Halal)

Grilled chicken, onions, Alfredo sauce, feta cheese, & mozzarella cheese.
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Spinach Alfredo (Halal)

Spinach, onions, Alfredo sauce, feta cheese, & mozzarella cheese.
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Home Style Lasagna (Halal)

Fresh pasta layered with meat and cheese served with garlic bread.
$10.99
Spaghetti (Halal)

Your choice of meatballs or chicken with zesty marinara sauce & served with our fresh garlic bread.
$8.99
Chicken Parmesan (Halal)

$7.95
Meatball Sub (Halal)

Italian meatballs with meat sauce, and mozzarella cheese.
$8.95

DESSERTS
Fresh-baked Chocolate-chip Cookie

Soft Bakery Style Chocolate Chip Cookie!
$0.99
Italian Cannoli

Home-made Cannoli!
$2.75
New York Cheesecake

Best New York Cheesecake Ever!!!
$3.50
Strawberry Cheesecake

Best Strawberry Cheesecake Ever!!!
$3.50
Chocolate Cheesecake

Best Chocolate Cheesecake Ever!!!
$3.50
Italian Cream Cake

$3.50
Carrot Cake

$3.50
Birthday Cake Truffle

Birthday cake ice cream covered in white chocolate with blue drizzle dipped in sprinkles.
$4.99
Cookies & Cream Truffle

Cookies and cream ice cream enrobed in dark chocolate with dark chocolate drizzle.
$4.99
Mango Sorbet Truffle

Fresh fruit mango sorbet in real mango shell.
$4.99
Pistachio Truffle

Pistachio ice cream enrobed in white chocolate with green drizzle.
$4.99
Vanilla Peanut Butter Truffle

Vanilla ice cream with peanut butter swirls and a rich creamy peanut butter center. Enrobed in milk chocolate with a milk chocolate drizzle.
$4.99
Cappuccino Commotion Gelate Truffle

Cappuccino gelate with chocolate chips enrobed in dark chocolate with milk chocolate drizzle.
$4.99
Chocolate Chip Mint Truffle

Mint chocolate ice cream with fudge center enrobed in dark chocolate with dark chocolate drizzle.
$4.99
White Chocolate Parisianne Truffle

White chocolate ice cream with raspberry sorbet center enrobed in white chocolate with red drizzle.
$4.99
Mom's Coconut Gelato Truffle

Coocnut gelato with a mango sorbet center enrobed in coconut and half dipped in dark chocolate with dark chocolate drizzle.
$4.99

BEVERAGES
Can Soda

Pepsi, Diet Pepsi, Dr. Pepper, 7-UP, Sierra Mist, Big Red, Root Beer
$0.99
Bottled Soda

Pepsi, Diet Pepsi, Dr. Pepper, 7-UP, Sierra Mist, Big Red, Root Beer
$1.69
Bubbly Sparking Water

$1.99
LIFE WTR

$2.19
Pure Leaf Tea

Pure Leaf Unsweetened Black Tea, Pure Leaf Peach Tea, Pure Leaf Sweet Tea
$2.49
2-Liter Soda

Pepsi, Diet Pepsi, Dr. Pepper, 7-UP, Sierra Mist, Big Red, Root Beer
$3.39
Monster

$2.99
Red Bull

$3.39
Vanilla (Starbucks)

$2.69
Mocha (Starbucks)

$2.69
Water Bottle

$1.69
Two Guys Pizzeria
Located near the intersection of Greenbriar Dr. and West Holcombe Blvd. in the Medical Center Plaza of West Holcombe, Two Guys Pizzeria has become a neighborhood haven for amazing, hand-tossed pizzas, wings, subs and salads. At Two Guys, we use only the finest toppings and ingredients and never skimp on quality. Our huge selection of specialty pies include classic favorites like Margherita and Hawaiian pizza and also include Two Guys originals like our famous J & J Special--made with Pepperoni, feta cheese, fresh mushrooms, fresh garden tomatoes, mozzarella cheese and our house made pizza sauce. Add a side of Beef and Jalapeno Pizza Rolls and a Garden Salad and you have yourself a meal the entire family will enjoy. Order Two Guys Pizzeria Online Today for Carryout or Delivery!97%
of 461 customers recommendedHours of Business
Sunday and Monday
11:00 AM - 9:00 PM
Su,Mo 11:00-21:00
Tuesday - Saturday
11:00 AM - 10:00 PM
Tu,We,Th,Fr,Sa 11:00-22:00
Carryout Hours
Sunday and Monday
11:00 AM - 8:30 PM
Tuesday - Saturday
11:00 AM - 9:30 PM
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Pizza,Salads,Sandwiches,Calzones,Subs,Wings,Pasta